Rare Gastroenterology News

5 Facts you should know about

Autoimmune hepatitis



Autoimmune hepatitis may present as completely asymptomatic

(12–35% of the cases), with signs of chronic liver disease, or acute or even fulminant hepatic failure.


Common initial symptoms include fatigue or muscle aches

or signs of acute liver inflammation including fever, jaundice, and right upper quadrant abdominal pain.


The disease may occur in any ethnic group and at any age,

but is most often diagnosed in patients between 40 and 50 years of age.


Anomalous presentation of MHC class II receptors on the surface of liver cells

causes a cell-mediated immune response against the body's own liver, resulting in autoimmune hepatitis.


Virtually all patients have increased circulating IgG levels.

Rare Gastroenterology News